HR Excellence in Science
Total found: 41 records
Matoušková Z., Orsághová K., Srb P., Pytelková J., Kukačka Z., Buša M., Hajdušek O., Šíma R., Fábry M., Novák P., Horn M., Kopáček P., Mareš M. (2024) An unusual two-domain thyropin from tick saliva: NMR solution structure and highly selective inhibition of cysteine cathepsins modulated by glycosaminoglycans International Journal of Molecular Sciences 25: 2240.
DOI: 10.3390/ijms25042240
Klouwens M.J., Trentelman J.J.A., Barriales D., Ersoz J.I., Azkargorta M., Elortza F., Šíma R., Hajdušek O., Lavin J.L., Tomás-Cortázar J., Escobes Corcuera I., Colstrup E., Nayak A., Ruíz M.I., Rodriguez H., Nijhof A., Anguita J., Hovius J.W.R. (2023) The Ixodes ricinus salivary gland proteome during feeding and B. Afzelii infection: New avenues for an anti-tick vaccine Vaccine 41: 1951–1960.
DOI: 10.1016/j.vaccine.2023.02.003
Kozelková T., Dyčka F., Lu S., Urbanová V., Frantová H., Sojka D., Šíma R., Horn M., Perner J., Kopáček P. (2023) Insight into the dynamics of the Ixodes ricinus nymphal midgut proteome Molecular and Cellular Proteomics 22: 100663.
DOI: 10.1016/j.mcpro.2023.100663
Wu-Chuang A., Mateos-Hernández L., Maitre A., Rego R. O. M., Šíma R., Porcelli S., Rakotobe S., Foucault-Simonin A., Moutailler S., Palinauskas V., Aželytė J., Šimo L., Obregon D., Cabezas-Cruz A. (2023) Microbiota perturbation by anti-microbiota vaccine reduces the colonization of Borrelia afzelii in Ixodes ricinus Microbiome 11: 151.
DOI: 10.1186/s40168-023-01599-7
Perner J., Kučera M., Frantová H., Urbanová V., Kopáček P., Šíma R. (2022) Lyme disease transmission by severely impaired ticks Open Biology 12: 210244.
DOI: 10.1098/rsob.210244
Trentelman J.J.A., de Vogel F.A., Colstrup E., Šíma R., Coumou J., Koetsveld J., Klouwens M.J., Nayak A., Ersoz J., Barriales D., Tomás-Cortázar J., Narasimhan S., Hajdušek O., Anguita J., Hovius J. (2022) Identification of novel conserved Ixodes vaccine candidates; a promising role for non-secreted salivary gland proteins Vaccine 40: 7593–7603.
DOI: 10.1016/j.vaccine.2022.10.032
Urbanová V., Kalinová Kalinová, Kopáček P., Šíma R. (2022) Experimental infection of mice and ticks with the human isolate of Anaplasma phagocytophilum NY-18 Pathogens 11: 820.
DOI: 10.3390/pathogens1107082
Klouwens M.J., Trentelman J.J., Ersoz J.I., Nieves Marques Porto F., Šíma R., Hajdušek O., Thakur M., Hovius J. (2021) Investigating BB0405 as a novel Borrelia afzelii vaccination candidate in Lyme borreliosis Scientific Reports 11: 4775.
DOI: 10.1038/s41598-021-84130-y
Kopáček P., Šíma R., Perner J. (2021) An mRNA-based anti-tick vaccine catches ticks red-handed Science Translational Medicine 13eabm2504: eabm2504.
DOI: 10.1126/scitranslmed.abm2504
Mahmood S., Šíma R., Urbanová V., Trentelman J.J., Krezdorn N., Winter P., Kopáček P., Hovius J., Hajdušek O. (2021) Identification of Tick Ixodes ricinus Midgut Genes Differentially Expressed During the Transmission of Borrelia afzelii Spirochetes Using a Transcriptomic Approach Frontiers in Immunology 11: 612412.
DOI: 10.3389/fimmu.2020.612412
Šíma R. (2021) Kdo probudí borelii Vesmír 7: 464.
Trentelman J., Tomás-Cortázar J., Knorr S. , Barriales D., Hajdušek O., Šíma R., Ersoz J.I., Narasimhan S., Fikrig E., Nijhof A., Anguita J., Hovius J. (2021) Probing an Ixodes ricinus salivary gland yeast surface display with tick-exposed human sera to identify novel candidates for an anti-tick vaccine Scientific Reports 11: 15745.
DOI: 10.1038/s41598-021-92538-9
Gobl J., Sinha , Šíma R., Perner J., Kopáček P., Valdés J. J., Rego R. O. M., Cabezas-Cruz A. (2020) Histone Methyltransferase DOT1L Is Involved in Larval Molting and Second Stage Nymphal Feeding in Ornithodoros moubata Vaccines 8: 157.
DOI: 10.3390/vaccines8020157
Kamp H.D., Swanson K.A., Wei R.R., Dhal P.K., Dharanipragada R., Kern A., Sharma B., Šíma R., Hajdušek O., Hu L.T., Wei Ch.-J., Nabel G.J. (2020) Design of a broadly reactive Lyme disease vaccine npj Vaccines 5: 33.
DOI: 10.1038/s41541-020-0183-8
Mateos-Hernández L., Defaye B., Vancová M., Hajdušek O., Šíma R., Park Y., Attoui H., Šimo L. (2020) Cholinergic axons regulate type I acini in salivary glands of Ixodes ricinus and Ixodes scapularis ticks Scientific Reports 10: 16054.
DOI: 10.1038/s41598-020-73077-1
Trentelman J.J., Šíma R., Krezdorn N., Tomás-Cortázar J., Barriales D., Takumi K., Butler J.M., Sprong H., Klouwens M.J., Urbanová V., Mahmood S., Winter P., Kopáček P., Anguita J., Hajdušek O., Hovius J. (2020) A combined transcriptomic approach to identify candidates for an anti-tick vaccine blocking B. afzelii transmission Scientific Reports 10: 20061.
DOI: 10.1038/s41598-020-76268-y
Korytář T., Wiegertjes G.F., Zusková E., Tomanová A., Lisnerová M., Patra S., Sieranski V., Šíma R., Born-Torrijos A., Wentzel A.S., Blasco-Monleon S., Yanes-Roca C., Policar T., Holzer A. (2019) The kinetics of cellular and humoral immune responses of common carp to presporogonic development of the myxozoan Sphaerospora molnari Parasites & Vectors 12: 208.
DOI: 10.1186/s13071-019-3462-3
Kosakyan A., Alama Bermejo G., Bartošová-Sojková P., Born-Torrijos A., Šíma R., Nenarokova A., Eszterbauer E., Bartholomew J., Holzer A. (2019) Selection of suitable reference genes for gene expression studies in myxosporean (Myxozoa, Cnidaria) parasites. Scientific Reports 9: 15073.
DOI: 10.1038/s41598-019-51479-0

Documents to download:
Kosakyan_2019_ScientReport (pdf)
Pospíšilová Pospíšilová, Urbanová V., Hes O., Kopáček P., Hajdušek O., Šíma R. (2019) Tracking of Borrelia afzelii transmission from infected Ixodes ricinus nymphs to mice Infection and Immunity 87: e00896-18.
DOI: 10.1128/IAI.00896-18
Rego R. O. M., Trentelman J.J., Anguita J., Nijhof A., Sprong H., Klempa B., Hajdušek O., Tomás-Corázar J., Azagi T., Strnad M., Knorr S. , Šíma R., Jalovecká M., Havlíková S., Ličková M., Sláviková M., Kopáček P., Grubhoffer L., Hovius J. (2019) Counterattacking the tick bite: towards a rational design of anti-tick vaccines targeting pathogen transmission Parasites & Vectors 12: 229.
DOI: 10.1186/s13071-019-3468-x

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