Mission

Laboratory of Tick transmitting diseases (founded in 2012) is focused on the molecular interaction between ticks (e.g., iron and heme metabolism pathway, tick immune molecules) and tick transmitting pathogens and testing of anti-tick vaccines (improvement of our recent vaccine based on the protein called Ferritin 2) and vaccines interfering with the pathogen transmission. We have set-up in our laboratory (BSL2) complete transmission model for Borrelia infections, which we use for testing of the tick candidate genes implicated in the interaction of tick-parasite by the method of RNA interference (RNAi) and also vaccines blocking the pathogen transmission. Recently, we make an effort to set-up a system for testing infections of Babesia and Anaplasma.

Česká verze: http://www.paru.cas.cz/cs/sekce/klistata-a-jimi-prenasene-nemoci/laborator-klistaty-prenasenych-onemocneni/