Research

 Research of the Department of Molecular Genetics focuses on viroid research, functional genomics of hop, antisensing and gene silencing, anti-tumoric plant nucleases, and virus variability.

Viroid research

• Focused on PSTVd and hop viroids
• Study on biochemical aspects of viroid-caused pathogenesis, propagation, antisensing and variability
• Analysis of adaptability, evolution and variability under stress conditions
• Induction and mechanisms of paralyzing effects caused by viroids
• Transfer of viroid populations to weed species and probing viroid elimination processes

Functional genomics of hop

• Genomic and expression libraries focused on genes co-determining lupulin productions
• Isolation and characterization hop transcription factors and their complexes
• Analysis of transcrition factors network determining biosynthesis of medicinal prenylchalcones

Anti-tumorogenic plant nuclease

• Molecular genetic analysis of plant nuclease I and its homologues as a source for for medicinal experiments, analysis of anticancer action
• Clonning and comparative functional genomics and proteomics of plant nucleases and nuclease biogenesis
• Recombinant plant nucleases preparation, structure analysis and modifications